Do you have finger and/or thumb joint pain caused by hand osteoarthritis?
Welcome to the HOPE-e study website.
We are inviting women aged 40-65, who are at least 1 year after menopause, and are experiencing hand pain due to osteoarthritis (OA), to take part in this study.
Purpose of the study: We want to test whether taking a tablet of an estrogen-containing therapy once daily for 6 months improves hand pain in women with hand OA, when compared with taking a placebo tablet (inactive medication). This study aims to find out whether it is acceptable to women with painful hand OA to take this type of treatment, and also what the best way of collecting some of the information is, to help us plan a full size trial. The study may also give us some idea of whether this treatment might work or not.
If you are interested in taking part in this study or would like more information, please contact the study team.
The HOPE-e study is now open to recruitment!
13 June 2019: White Horse Medical Centre (Faringdon) open to recruitment for registered patients.
24 May 2019: Our second site, Charing Cross Hospital, opens to recruitment.
09 May 2019: HOPE-e opens to recruitment! The first site to open is the Nuffield Orthopaedic Centre, Oxford.
The HOPE-e study is being led and managed by the Oxford Clinical Trials Research Unit (OCTRU) in collaboration with the University of Oxford and Oxford University Hospitals NHS Trust.
The National Institute for Health Research (NIHR) is funding this study, via their ‘Research for Patient Benefit’ programme. The study also benefits from resources including staff time provided by the Centre for OA Pathogenesis Versus Arthritis, which is based in Oxford.
